Inyo County was formed in 1866 from the territory of the unorganized Coso County created on April 4, 1864 from parts of Mono and Tulare Counties. It acquired more territory from Mono County in 1870 and Kern County and San Bernardino County in 1872.

Inyo was the name of the headman of the Panamint band of Paiute-Shoshone. The Owens Valley whites misunderstood the local Paiute and thought that Inyo was the name of the mountains when actually it was the name of the chief, of the tribe that had those mountains as part of their homeland.

In order to provide water needs for the growing City of Los Angeles, water was diverted from the Owens River into the Los Angeles Aqueduct in 1913. The Owens River Valley cultures and environments changed substantially. From the 1910s to 1930s the Los Angeles Department of Water and Power purchased much of the valley for water rights and control. In 1941 the Los Angeles Department of Water and Power extended the Los Angeles Aqueduct system further upriver into the Mono Basin.

NameNational LandmarkState LandmarkPoint of InterestOther Designation
San Francis RanchN/A208N/AN/A
Site of Bend CityN/A209N/AN/A
Mayfield Canyon BattlegroundN/A211N/AN/A
Site of Putnam’s CabinN/A223N/AN/A
Mary Austin’s HomeN/A229N/AN/A
First Permanent White Habitation in Owens ValleyN/A230N/AN/A
Camp IndependenceN/A349N/AN/A
Burned Wagons PointN/A441N/AN/A
Death Valley GatewayN/A442N/AN/A
Valley WellsN/A443N/AN/A
Bennett Arcane Long CampN/A444N/AN/A
Grave of 1872 Earthquake VictimsN/A507N/AN/A
Cottonwood Charcoal KilnN/A537N/AN/A
Furnace of the Owens Lake Silver-Lead CompanyN/A752N/AN/A
Old Harmony Borax WorksN/A773N/AN/A
Farleys Olancha Mill SiteN/A796N/AN/A
Bishop Creek BattlegroundN/A811N/AN/A
Old Stovepipe WellsN/A826N/AN/A
Eichbaum Toll RoadN/A848N/AN/A
Manzanar76000484850N/ACity of Los Angeles Cultural-Historic Landmark (#160)
National Monument
Laws Narrow Gauge Railroad Station and Yard81000149953N/AN/A
Alabama GatesN/AN/APoint of InterestN/A
Roosevelt TreeN/AN/APoint of InterestN/A
Ancient Bristlecone Pine ForestN/AN/APoint of InterestN/A
Fossil FallsN/AN/APoint of InterestN/A
BallaratN/AN/APoint of InterestN/A
Cerro GordoN/AN/APoint of InterestN/A
DarwinN/AN/APoint of InterestN/A
Panamint CityN/AN/APoint of InterestN/A
Death Valley Junction and Amargosa Opera HouseN/AN/APoint of InterestN/A
Eastern California MuseumN/AN/APoint of InterestN/A
Father Crowley PointN/AN/APoint of InterestN/A
Shorty's GraveN/AN/APoint of InterestN/A
Badwater BasinN/AN/APoint of InterestN/A
Cartago Boat LandingN/AN/APoint of InterestN/A
Dante's ViewN/AN/APoint of InterestN/A
Devil's Golf CourseN/AN/APoint of InterestN/A
Eastern Sierra Interagency Visitor CenterN/AN/APoint of InterestN/A
El Camino Sierra and Old Highway 23N/AN/APoint of InterestEl Camino Sierra
Furnace Creek Visitor CenterN/AN/APoint of InterestN/A
Golden CanyonN/AN/APoint of InterestN/A
Hell's GateN/AN/APoint of InterestN/A
Kearsarge StationN/AN/APoint of InterestN/A
Skidoo PipelineN/AN/APoint of InterestN/A
Ubehebe CraterN/AN/APoint of InterestN/A
Wildrose Charcoal KilnsN/AN/APoint of InterestN/A
Zabriske's PointN/AN/APoint of InterestN/A
Inyo National ForestN/AN/AN/ANational Forest
Death ValleyN/AN/AN/ANational Park